Search_Gene

Query Gene
Gene name: Example: BCL2L11, ERCC1

Symbol:

ADAM17

Description:

ADAM metallopeptidase domain 17 [Source:HGNC Symbol;Acc:195]

Location:

Chr2:9628615-9695921[-]

CRmiRSNP:

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Records:45

Compound	CRmiRSNP	SNP_sig	Model	Molecule	Mol_sig	Type
NSC 119621	rs1130094	0.001015001	M1	ADAM17	0.008	Target_3'utr
NSC 144151	rs1130094	0.02546939	M1	ADAM17	0.008	Target_3'utr
NSC 267461	rs1130094	0.04788611	M1	ADAM17	0.002	Target_3'utr
NSC 603071	rs1130094	0.01260313	M1	ADAM17	0.049	Target_3'utr
NSC 617566	rs1130094	0.04126037	M1	ADAM17	0.005	Target_3'utr
NSC 623925	rs1130094	0.04287362	M1	ADAM17	0.001	Target_3'utr
NSC 637467	rs1130094	0.04368182	M1	ADAM17	0.003	Target_3'utr
NSC 645392	rs1130094	0.000889049	M1	ADAM17	0.045	Target_3'utr
NSC 657181	rs1130094	0.001424026	M1	ADAM17	0.005	Target_3'utr
NSC 657321	rs1130094	0.03059263	M1	ADAM17	0.001	Target_3'utr
NSC 669308	rs1130094	0.004226502	M1	ADAM17	0.006	Target_3'utr
NSC 669450	rs1130094	0.006018875	M1	ADAM17	0.011	Target_3'utr
NSC 669608	rs1130094	0.023347	M1	ADAM17	0.021	Target_3'utr
NSC 671190	rs1130094	4.16E-05	M2	ADAM17	0.034	Target_3'utr
NSC 671898	rs1130094	0.02356384	M1	ADAM17	0.02	Target_3'utr

Model : M1-Allele, M2-Recessive, M3-Additive, M4-Dominant
Total:3 Current:1 [First] [Prev] Next Last

Compound:

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Records:307

Gene	Compound	Gen_sig	Exp_pattern
ADAM17	NSC 735333	0.018	Up
ADAM17	NSC 736104	0.015	Up
ADAM17	NSC 736154	0.003	Up
ADAM17	1,2-Dithiolan-3-yl-N-(3'-methoxyestra-1',3',5'(10')-triene-1 7'b-yl)pentanamide	0.027	Up
ADAM17	6-[3-[2-[1,2,4]-Triazolyl-1-propyl]-5,6-dihydro-2,3-dimethox y-8,9-methylenedioxy-5,11-dioxo-11H-indeno[1,2-c]isoquinolin e Hydrochloride	0.017	Down
ADAM17	6-(3-fluoro-4-methoxyphenyl)-5-(3,4,5-trimethoxyphenyl)-2H-pyran-2-one	0.048	Up
ADAM17	12-Benzyl-5,12-dihydro-indeno[2',1':4,5]pyrrolo[3,2-c]chinolin-6,7-dione	0.004	Down
ADAM17	BAS100 Monohydrate	0.016	Up
ADAM17	2-{4-[4-(4-{4-[6-(4-methyl piperazino)-1H-benzo[d]imidazole-2-yl]phenoxy}butyl)piperazino]butyl}-2,3-dihydro-1H-benzo[de]isoquinoline-1,3-dione	0.049	Up
ADAM17	NSC 743557	0.02	Up
ADAM17	NSC 743694	0.032	Up
ADAM17	NSC 746316	0.041	Up
ADAM17	7-{[3-(dibutylamino)propyl]amino}-5-imino-1,3,6-triphenyl-5,6-dihydropyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dithione	0.018	Up
ADAM17	NSC 747174	0.034	Up
ADAM17	NSC 747452	0.021	Up

Expression pattern: Sensitivity / Resistance
Total:21 Current:20 First Prev Next Last

SNP:

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Records:14

SNP	Gene	SNP_location	SNP_allele
rs144681167	ADAM17	Chr2:9629546	-/AGTA
rs71636812	ADAM17	Chr2:9629548	-/GTAA
rs192681806	ADAM17	Chr2:9629625	T/A
rs184660941	ADAM17	Chr2:9629719	T/C
rs10063	ADAM17	Chr2:9629731	T/C
rs139684774	ADAM17	Chr2:9629774	C/T
rs189060518	ADAM17	Chr2:9629874	A/C
rs77130641	ADAM17	Chr2:9629878	ACTA/-
rs73149881	ADAM17	Chr2:9629926	C/T
rs111759422	ADAM17	Chr2:9629943	-/A
rs5829218	ADAM17	Chr2:9629945	-/A
rs1130094	ADAM17	Chr2:9630016	T/C
rs6705408	ADAM17	Chr2:9630231	C/T
rs3833563	ADAM17	Chr2:9630245	T/-

Total:1 Current:1 [First] [Prev] [Next] [Last]

miRNA:

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Records:32

Gene	Gen_transcript	miRNA	miR_location
ADAM17	ENST00000310823	hsa-mir-105-5p	ChrX:151560737-151560759[-]
ADAM17	ENST00000342158	hsa-mir-105-5p	ChrX:151560737-151560759[-]
ADAM17	ENST00000310823	hsa-mir-105-5p	ChrX:151562930-151562952[-]
ADAM17	ENST00000342158	hsa-mir-105-5p	ChrX:151562930-151562952[-]
ADAM17	ENST00000310823	hsa-mir-140-3p	Chr16:69967045-69967065[+]
ADAM17	ENST00000342158	hsa-mir-140-3p	Chr16:69967045-69967065[+]
ADAM17	ENST00000342158	hsa-mir-146b-5p	Chr10:104196277-104196298[+]
ADAM17	ENST00000310823	hsa-mir-183-3p	Chr7:129414768-129414789[-]
ADAM17	ENST00000310823	hsa-mir-194-5p	Chr11:64658876-64658897[-]
ADAM17	ENST00000342158	hsa-mir-194-5p	Chr11:64658876-64658897[-]
ADAM17	ENST00000310823	hsa-mir-194-5p	Chr1:220291548-220291569[-]
ADAM17	ENST00000342158	hsa-mir-194-5p	Chr1:220291548-220291569[-]
ADAM17	ENST00000310823	hsa-mir-222-5p	ChrX:45606479-45606500[-]
ADAM17	ENST00000342158	hsa-mir-222-5p	ChrX:45606479-45606500[-]
ADAM17	ENST00000310823	hsa-mir-32-3p	Chr9:111808511-111808532[-]

Total:3 Current:1 [First] [Prev] Next Last