Statistics

  • Compound:1164
  • SNP:126757
  • miRNA:319
  • Gene:17625
  • CRmiRSNP:150

Query Gene
Gene name:

Example:  BCL2L11,  ERCC1
Symbol: DOT1L
Description: DOT1-like, histone H3 methyltransferase (S. cerevisiae) [Source:HGNC Symbol;Acc:24948]
Location: Chr19:2164148-2232577[+]
CRmiRSNP:

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Records:null
Compound CRmiRSNP SNP_sig Model Molecule Mol_sig Type
Model : M1-Allele, M2-Recessive, M3-Additive, M4-Dominant
Total:0 Current:1  [First] [Prev] [Next] [Last] 
Compound:

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Records:432
Gene Compound Gen_sig Exp_pattern
DOT1L NSC 727259 0.032 Down
DOT1L NSC 732719 0.015 Down
DOT1L NSC 732956 0.029 Down
DOT1L NSC 733155 0.014 Down
DOT1L NSC 734631 0.018 Down
DOT1L 4-(4-Chloro-phenyl)-7a-methyl-2,5-diphenyl-7aH-cyclopenta[b] pyran-7-one 0.001 Down
DOT1L 6-(3-Bromopropyl)-5,6-dihydro-9-methyl-3-nitro-5,11-dioxo-11 H-indeno[1,2-c]isoquinoline 0.031 Down
DOT1L NSC 736104 0.027 Down
DOT1L NSC 736154 0.001 Down
DOT1L 1,2-Dithiolan-3-yl-N-(3'-methoxyestra-1',3',5'(10')-triene-1 7'b-yl)pentanamide 0.011 Down
DOT1L NSC 736189 0.032 Up
DOT1L 2-(4-chloro-2-methylphenoxy)-N-(4-chlorobenzo[d]thiazol-2-yl )acetamide 0.001 Down
DOT1L 7-(2-Pyrrolidinoethyl)oximino-5-androsten-3b,17b-diol diacetate 0.038 Down
DOT1L 6-(3-Chloropropyl)-5,6-dihydro-2,3,9-trimethoxy-5,11-dioxo-1 1H-indeno[1,2-c]isoquinoline 0.026 Down
DOT1L 1-(4-chlorophenyl)-3,3-diphenyl-1'-methylspiro[azetidin-2,3' =indoline]=2',4-dione 0.001 Down
Expression pattern: Sensitivity / Resistance
Total:29 Current:27  First Prev Next Last 
SNP:

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Records:61
SNP Gene SNP_location SNP_allele
rs117747984 DOT1L Chr19:2229808 G/A
rs145796620 DOT1L Chr19:2229864 C/T
rs190867751 DOT1L Chr19:2229936 C/T
rs182290621 DOT1L Chr19:2229943 C/T
rs150147737 DOT1L Chr19:2230030 TT/-
rs148986997 DOT1L Chr19:2230044 C/G
rs143685653 DOT1L Chr19:2230130 C/T
rs138329274 DOT1L Chr19:2230233 C/T
rs112656439 DOT1L Chr19:2230303 A/G
rs185888752 DOT1L Chr19:2230314 C/T
rs142895997 DOT1L Chr19:2230349 C/G
rs62119663 DOT1L Chr19:2230422 G/T
rs34851161 DOT1L Chr19:2230448 G/-
rs144983547 DOT1L Chr19:2230451 G/A
rs34699319 DOT1L Chr19:2230543 C/T
Total:5 Current:1  [First] [Prev] Next Last 
miRNA:

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Records:36
Gene Gen_transcript miRNA miR_location
DOT1L ENST00000221482 hsa-mir-125b-5p Chr11:121970517-121970538[-]
DOT1L ENST00000221482 hsa-mir-125b-5p Chr21:17962573-17962594[+]
DOT1L ENST00000221482 hsa-mir-140-3p Chr16:69967045-69967065[+]
DOT1L ENST00000221482 hsa-mir-146b-3p Chr10:104196313-104196334[+]
DOT1L ENST00000221482 hsa-mir-18a-3p Chr13:92003051-92003073[+]
DOT1L ENST00000221482 hsa-mir-193a-3p Chr17:29887069-29887090[+]
DOT1L ENST00000221482 hsa-mir-193b-5p Chr16:14397837-14397858[+]
DOT1L ENST00000221482 hsa-mir-222-5p ChrX:45606479-45606500[-]
DOT1L ENST00000221482 hsa-mir-224-5p ChrX:151127103-151127123[-]
DOT1L ENST00000221482 hsa-mir-324-3p Chr17:7126627-7126646[-]
DOT1L ENST00000221482 hsa-mir-339-3p Chr7:1062591-1062613[-]
DOT1L ENST00000221482 hsa-mir-34a-5p Chr1:9211794-9211815[-]
DOT1L ENST00000221482 hsa-mir-34c-5p Chr11:111384176-111384198[+]
DOT1L ENST00000221482 hsa-mir-449a Chr5:54466414-54466435[-]
DOT1L ENST00000221482 hsa-mir-449b-5p Chr5:54466534-54466555[-]
Total:3 Current:1  [First] [Prev] Next Last