Query Small Molecule
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Small Moleccule Name List
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Name: isotretinoin
DrugBank ID: DB00982
Structure:
Description: Isotretinoin is a medication used for the treatment of severe acne. It is sometimes used in prevention of certain skin cancers. It is a retinoid, meaning it derives from vitamin A and is found in small quantities naturally in the body. Isotretinoin binds to and activates nuclear retinoic acid receptors (RAR), thereby regulating cell proliferation and differentiation. This agent also exhibits immunomodulatory and anti-inflammatory responses and inhibits ornithine decarboxylase, thereby decreasing polyamine synthesis and keratinization.
Association:   figure  
Small molecule miRNA P-value Correlation
isotretinoin hsa-miR-382 0.03062 negative
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