Name:	nifedipine
DrugBank ID:	DB01115
Structure:
Description:	Nifedipine has been formulated as both a long- and short-acting 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nifedipine prevents calcium-dependent myocyte contraction and vasoconstriction. A second proposed mechanism for the drug’s vasodilatory effects involves pH-dependent inhibition of calcium influx via inhibition of smooth muscle carbonic anhydrase. Nifedipine is used to treat hypertension and chronic stable angina.
Association:   figure	Small molecule miRNA P-value Correlation nifedipine hsa-miR-368 0.0222 positive TotalPage:1, CurrentPage:1  First  Prev Next  Last