Name:	nimodipine
DrugBank ID:	DB00393
Structure:
Description:	Nimodipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. Compared to other calcium channel blocking agents, nimodipine exhibits greater effects on cerebral circulation than on peripheral circulation. Nimodipine is used to as an adjunct to improve the neurologic outcome following subarachnoid hemorrhage from ruptured intracranial aneurysm.
Association:   figure	Small molecule miRNA P-value Correlation nimodipine hsa-miR-320 0.02381 positive nimodipine hsa-miR-601 0.02678 positive nimodipine hsa-miR-30e-5p 0.02721 positive TotalPage:1, CurrentPage:1  First  Prev Next  Last