Name:	zidovudine
DrugBank ID:	DB00495
Structure:
Description:	A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription. It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves certain other clinical abnormalities associated with AIDS. Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia. [PubChem]
Association:   figure	Small molecule miRNA P-value Correlation zidovudine hsa-miR-368 0.00448 negative zidovudine hsa-miR-575 0.04152 negative TotalPage:1, CurrentPage:1  First  Prev Next  Last